Toward Integrative Omics
Cancer is incredibly complex, posing enormous challenges beyond the biological field. Taking a multi-omic approach can help us make sense of this diverse set of diseases – and, ultimately, allow us to better understand ourselves as human beings.
Amanda Hummon |
I started researching colorectal cancer for multiple reasons, but a significant part of my interest was triggered by grief; a member of my immediate family died as a result of metastatic colorectal cancer, despite having the access to the best medical care. I wanted to understand more of what had happened and why.
At a Glance
- No one field of –omics is sufficient to understand cancer; we need to look at not just the genome or the transcriptome, but the metabolome, proteome, lipidome and others too
- Next generation sequencing drives genomic advances, but recent improvements in mass spectrometry are driving proteomics
- To derive the greatest benefit from new technologies, we must use them in conjunction with smart data analysis tools like database searching algorithms
- Other “–omes” are poised at the edge of advancement and will grow exponentially as our ability to analyze the data improves
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