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Diagnostics Oncology, Genetics and epigenetics, Omics, Biochemistry and molecular biology

Toward Integrative Omics

I started researching colorectal cancer for multiple reasons, but a significant part of my interest was triggered by  grief; a member of my immediate family died as a result of metastatic colorectal cancer, despite having the access to the best medical care. I wanted to understand more of what had happened and why.

At a Glance

  • No one field of –omics is sufficient to understand cancer; we need to look at not just the genome or the transcriptome, but the metabolome, proteome, lipidome and others too
  • Next generation sequencing drives genomic advances, but recent improvements in mass spectrometry are driving proteomics
  • To derive the greatest benefit from new technologies, we must use them in conjunction with smart data analysis tools like database searching algorithms
  • Other “–omes” are poised at the edge of advancement and will grow exponentially as our ability to analyze the data improves

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About the Author

Amanda Hummon

Amanda Hummon is Associate Professor in the Department of Chemistry and Biochemistry, University of Notre Dame, USA.

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