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The Pathologist / Issues / 2021 / Nov / The Rise of Analytical Science
Microbiology & Immunology Analytical science Microbiology and Immunology

The Rise of Analytical Science

Methods such as MALDI-TOF are opening new doors in the microbiology lab

By Wendy Szymczak 11/30/2021 Quick Read (pre 2022) 1 min read

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Specific to the clinical microbiology laboratory, we have seen major technologic advancements happen over the past decade. We’ve seen MALDI-TOF become routinely used for pathogen identification, increased use of multiplexed nucleic acid amplification tests, the emergence of rapid susceptibility platforms including a method that can be performed directly from positive blood culture bottles, and a system that uses magnetic resonance to identify bacteria and yeast directly from blood specimens. Most recently, we are beginning to see clinical laboratories adopt next-generation sequencing for pathogen detection, antimicrobial resistance prediction, and strain typing. These new technologies have allowed us to provide results in a more rapid and accurate manner, allowing for optimal patient management and treatment as quickly as possible.

– Wendy Szymczak

Learn more about Szymczak’s work at: tp.txp.to/infect-disease

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About the Author(s)

Wendy Szymczak

Director of the Clinical Microbiology Laboratory at Montefiore Medical Center and Associate Professor of Pathology at Albert Einstein College of Medicine, Bronx, New York, USA.

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