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The Pathologist / Issues / 2018 / Feb / Pixel Perfect
Analytical science Genetics and epigenetics Omics Molecular Pathology

Pixel Perfect

A spatial gene expression technique for improved tissue sample analysis

By William Aryitey 02/23/2018 1 min read

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Existing gene expression analysis tools, though accurate, are slow and cumbersome to use. Is this trade-off really necessary? Not according to a multidisciplinary group of researchers who incorporated the best of both worlds into a technique that performs on-chip tissue analysis in under two hours: pixelated RT-LAMP (reverse transcriptase loop mediated isothermal amplification). To find out more, we spoke to Anarup Ganguli, first author of the resulting publication (1) and research assistant at the University of Illinois at Urbana-Champaign, USA.

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References

  1. A Ganguli et al., “Pixelated spatial gene expression analysis from tissue”, Nat Commun, 9, (2018). PMID: 29335461.

About the Author(s)

William Aryitey

My fascination with science, gaming, and writing led to my studying biology at university, while simultaneously working as an online games journalist. After university, I travelled across Europe, working on a novel and developing a game, before finding my way to Texere. As Associate Editor, I’m evolving my loves of science and writing, while continuing to pursue my passion for gaming and creative writing in a personal capacity.

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