Existing gene expression analysis tools, though accurate, are slow and cumbersome to use. Is this trade-off really necessary? Not according to a multidisciplinary group of researchers who incorporated the best of both worlds into a technique that performs on-chip tissue analysis in under two hours: pixelated RT-LAMP (reverse transcriptase loop mediated isothermal amplification). To find out more, we spoke to Anarup Ganguli, first author of the resulting publication (1) and research assistant at the University of Illinois at Urbana-Champaign, USA.
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References
- A Ganguli et al., “Pixelated spatial gene expression analysis from tissue”, Nat Commun, 9, (2018). PMID: 29335461.