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The Pathologist / Issues / 2020 / Feb / Good Night!
Hematology Biochemistry and molecular biology Genetics and epigenetics Hematology Molecular Pathology

Good Night!

Sleep duration and microRNA expression levels are linked in children

By Luke Turner 02/27/2020 Quick Read (pre 2022) 1 min read

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Sleeping like a baby is not just key to maintaining productivity, concentration, and creativity; sleep duration can also affect susceptibility to a number of diseases, especially in children. But how can we measure sleep quality? New research has found a link between microRNA levels and sleep duration in children (1). “The expression levels of circulating miR-26b-3p and miR-485-5p are different between self-reported ‘short sleepers’ (children averaging less than nine hours) and ‘normal sleepers’ (children averaging more than nine hours)” says Fabio Lauria, co-author of the study.

“The notion that some circulating miRNAs display diurnal rhythmicity in healthy humans is a relatively novel finding (2) – and this study shows that sleep duration is reflected by the profile of specific circulating miRNAs in children and adolescents,” Lauria explains. With further research, this could pave the way for a simple blood test to assess sleep quality and, in turn, general health in children.

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References

  1. G Iacomino et al., Exp Physiol, 105, 347 (2020). PMID: 31916337.
  2. NH Heegaard et al., PLoS One, 11 (2016). PMID: 27494182.

About the Author(s)

Luke Turner

While completing my undergraduate degree in Biology, I soon discovered that my passion and strength was for writing about science rather than working in the lab. My master’s degree in Science Communication allowed me to develop my science writing skills and I was lucky enough to come to Texere Publishing straight from University. Here I am given the opportunity to write about cutting edge research and engage with leading scientists, while also being part of a fantastic team!

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