Using a macro-scanner to image larger samples with the detail of fluorescence microscopy
William Aryitey |
“Fluorescence microscopy is considered a minimally invasive optical technique to address a number of biological questions that cannot be answered by other means in a fast and relatively inexpensive way,” says Vladislav Shcheslavskiy, a senior research scientist at Becker & Hickl. “Although there are a lot of powerful methods to interrogate biological systems in vitro, there are a limited number of ways to explore samples in vivo, especially when they’re large.”
To overcome this difficulty, Shcheslavskiy and colleagues from Russia developed a system that allows users to boost fluorescence laser scanning microscopy to image samples as large as 18 mm² – where the previous limit was less than 1 mm². But what separates this technology from mainstream imaging techniques for large samples?
Read the full article now
Log in or register to read this article in full and gain access to The Pathologist’s entire content archive. It’s FREE and always will be!
Login if you already created an account
Or register now - it’s free and always will be!
You will benefit from:
- Unlimited access to ALL articles
- News, interviews & opinions from leading industry experts
- Receive print (and PDF) copies of The Pathologist magazine