Cookies

Like most websites The Pathologist uses cookies. In order to deliver a personalized, responsive service and to improve the site, we remember and store information about how you use it. Learn more.
Diagnostics Histology, Training and education

Case of the Month

A 53-year-old man presented with scrotal pain and a 1.5 cm testicular mass. Special stain for mucicarmine was negative. Immunohistochemistry (IHC) was negative for pancytokeratin, CK7, CK20, CDX2, inhibin, OCT-3/4, and chromogranin. What is the most likely diagnosis?

What is your diagnosis?

a. Leydig cell tumor
b. Sertoli cell tumor
c. Metastatic signet ring carcinoma from the colon
d. Primary signet ring stromal tumor of the testis

Click here to register your guess.

We will reveal the answer next month.

Do you have an interesting case that you would like us to feature? Email it to edit@thepathologist.com

Answer to May’s Case of the Month...

C. Mucoepidermoid carcinoma

This is a Warthin-like variant of mucoepidermoid carcinoma. At low power, the cystic nature of the process and the prominent lymphoid stroma are similar to Warthin’s tumor, but the classic bilayered oncocytic epithelium of that lesion is absent. There is no sebaceous type epithelium present, and the irregular, haphazard nature of the cystic spaces is somewhat unusual for sebaceous adenoma or lymphoepithelial cyst. In difficult cases, diagnosticians can pursue testing for the MAML2 translocation, which is present in mucoepidermoid carcinoma and absent in the other entities.

Submitted by Frank Ingram and Patrick Ware, Presbyterian Pathology Group, North Carolina, USA.

Enjoy our FREE content!

Log in or register to gain full unlimited access to all content on the The Pathologist site. It’s FREE and always will be!

Login

Or register now - it’s free and always will be!

You will benefit from:

  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Pathologist magazine
Register

Or Login via Social Media

By clicking on any of the above social media links, you are agreeing to our Privacy Notice.

Register to The Pathologist

Register to access our FREE online portfolio, request the magazine in print and manage your preferences.

You will benefit from:

  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Pathologist magazine

Register