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Diagnostics Biochemistry and molecular biology

Benchmarking Biomarkers of Myocardial Infarction

Cardiac biomarkers make up a diverse range of markers used in the diagnosis and risk assessment of patients with suspected acute coronary syndromes, including myocardial infarction (MI). According to the World Health Organization, in settings without resource constraints, observing pathological changes in cardiac serum biomarkers is an essential diagnostic criteria in cases of MI (1). Cardiac troponins are currently a widely used marker of choice, due to their high sensitivity in indicating damage to the myocardium.However, new and potential biomarkers are constantly being investigated, in the quest to accurately diagnose heart problems and identify those at risk – B-type natriuretic peptide and C-reactive protein are two examples of markers currently under investigation for future use in assessing cardiac pathologies.To provide insight into the past and predictions for the future of the field, a series of metrics were applied to the last five years of the published literature.

PubMed was searched for “myocardial infarction” and “biomarkers” with results limited to the last five years. The data were analyzed in Microsoft Excel 2013.

Top 20 Journals by Number of Publications
Publications by Country
Fee or Free
Top 20 Authors
Publications per Year
Most Researched Biomarkers. Articles in MEDLINE are indexed by Medical Subject Headings (MeSH) topics, that describe the articles’ main topics. Here are the top 6 most frequently mentioned biomarkers over the last five years of the myocardial infarction biomarker literature.
Top 20 Journals by Eigenfactor
Top 20 Journals by Impact Factor
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About the Author
Roisin McGuigan

I have an extensive academic background in the life sciences, having studied forensic biology and human medical genetics in my time at Strathclyde and Glasgow Universities. My research, data presentation and bioinformatics skills plus my ‘wet lab’ experience have been a superb grounding for my role as an Associate Editor at Texere Publishing. The job allows me to utilize my hard-learned academic skills and experience in my current position within an exciting and contemporary publishing company.

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