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ACD

Advanced Cell Diagnostics’ RNAscope® Technology is an in situ hybridization (ISH) assay for detection of target RNA within intact cells. The assay represents a major advance in RNA ISH approaches with its proprietary probe design to amplify target-specific signals but not background noise from non-specific hybridization. Unique to this technology, RNAscope® delivers quantitative, sensitive and specific molecular detection of RNA species on a cell-by-cell basis with morphological context in a single assay. This enables researchers to visualize which genes are expressed, localize where they are expressed, and quantify the level of expression.

Contact Information:

Advanced Cell Diagnostics SRL
Via Calabria, 15
20090 Segrate (Milano) Italy
Email: [email protected]
Phone: +39-02-95 360 323

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Content by ACD:

Diagnostics Genetics and epigenetics

The RNA Revolution

| Sponsored by ACD

A guide to RNA as a biomarker and its detection

The RNA Revolution

| Contributed by ACD

A Guide to RNA as a Biomarker and its Detection

Detection of immune cell checkpoint and functional markers in the tumor microenvironment by the RNA in situ hybridization RNAscope® assay

| Contributed by ACD

The RNAscope® assay is a unique RNA ISH technology that identifies RNA expression at the single cell level with morphological context.

Cellular localization of RNA expression in central and peripheral nervous system using RNAscope® Technology

| Contributed by ACD

Detect your RNA of interest in the central and peripheral nervous system with ease

Robust detection of RNA biomarkers for drug safety assessment in preclinical animal models by fully automated RNAscope® 2.5 LS Assay

| Contributed by ACD

Preclinical drug safety assessment in animal models is used to evaluate the pathological effects induced by novel therapeutic agents. Here we present the use of the RNAscope® 2.5 LS Assay for the evaluation of biomarkers in tissues from three preclinical animal models.

Specific Detection of Inflammation Markers with Tissue Context Using RNAscope® Technology

| Contributed by ACD

Understanding molecular mechanisms is critical for identifying pathogenesis, evaluating disease progression and developing new therapeutic strategies for autoimmunity, infectious diseases, and cancer.

Assess Transcriptionally Active HPV Biomarkers in Head and Neck Cancer Biopsies

| Contributed by ACD

Detect HPV E6/E7 mRNA expression with tissue morphological context

Specific Detection of RNA Expression and Distribution in Brain Using RNAscope® Technology

| Contributed by ACD

Detect RNA with ease

Detection of immune cell checkpoint and functional markers in the tumor microenvironment

| Contributed by ACD

No Antibody? No Problem!

| Contributed by ACD

RNAscope® RNA in situ hybridization technology

| Contributed by ACD

Webinars on Demand

Diagnostics Oncology

Elucidating Tumor Heterogeneity in Prostate Cancer by Combined IHC & Novel RNA ISH

| Sponsored by ACD

Assessment of molecular heterogeneity in tumor is a challenging task. For the first time, Palanisamy et al. have demonstrated the existence of a rare subset of prostate cancer with heterogeneous molecular aberrations involving ETS family genes and SPINK1 expression utilizing both standard immunohistochemistry (IHC) and RNA in situ hybridization (Advanced Cell Diagnostics RNAscope® Technology).

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