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New Biomarker Duo Predicts Colorectal Cancer Outcomes

Researchers found that p21 and epidermal growth factor receptor expression levels influence colorectal cancer prognosis.

By Kathryn Wighton 10/21/2025 News 2 min read

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  1. Study published in the Journal of Clinical Pathology.

  2. Investigated p21 and EGFR roles in CRC.

  3. Analyzed 12,319 CRC patients from 2008-2020.

  4. High p21 linked to longer survival; high EGFR linked to shorter survival.

  5. Used immunohistochemistry for biomarker quantification.

  6. Notable correlations found with tumor characteristics.

  7. Multivariate analysis identified significant prognostic factors.

About the Author(s)

Kathryn Wighton

Editor, Conexiant

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