Subscribe to Newsletter
Subspecialties Clinical care, Histology

Case of the Month

Recurrent Skin Tumor

Hematoxylin-eosin section (a) demonstrates a recurrent tumor from the leg of a 91-year-old man. The tumor was diagnosed two years previously as an angiosarcoma and treated by radical excision. The recurrent tumor avidly expressed CD31 and was nonreactive for smooth muscle actin, SOX-10, Melan A, and CD10. It was positive for HHV-8 (b).

What is the most likely diagnosis?

A. Angiosarcoma

B. Kaposiform hemangioendothelioma

C. Kaposi sarcoma

D. Spindle cell hemangioma

E. Spindle cell hemangioendothelioma

Click to register your guess

We will reveal the answer in next month’s issue!


Do you think you have a good case of the month? Email it to [email protected]

Answer to last month’s Case of the Month…

D: Yolk sac carcinoma

The tumor shows several histologic growth patterns, forming among others reticular, tubular and papillary structures, and even the so called Schiller-Duval bodies. The blood submitted to the laboratory after surgery contained increased amounts of alpha-fetoprotein.

Submitted by Da Zhang, The University of Kansas, Kansas City, USA.

Receive content, products, events as well as relevant industry updates from The Pathologist and its sponsors.
Stay up to date with our other newsletters and sponsors information, tailored specifically to the fields you are interested in

When you click “Subscribe” we will email you a link, which you must click to verify the email address above and activate your subscription. If you do not receive this email, please contact us at [email protected].
If you wish to unsubscribe, you can update your preferences at any point.

Register to The Pathologist

Register to access our FREE online portfolio, request the magazine in print and manage your preferences.

You will benefit from:
  • Unlimited access to ALL articles
  • News, interviews & opinions from leading industry experts
  • Receive print (and PDF) copies of The Pathologist magazine

Register