The Power of Pyrin

Researchers describe a new diagnostic tool for identifying familial Mediterranean fever

January 2017

Inflammation, fever, and severe pain – a combination of these symptoms that could be ascribed to a wide range of conditions, which is why patients with familial Mediterranean fever (FMF) can remain undiagnosed for years. But despite the difficulty in identifying it, FMF remains the most common monogenic autoinflammatory disease in the world. That’s why scientists at VIB Leuven and Ghent University have collaborated to create a diagnostic tool to detect it (1). To find out more about the test, we spoke with Mohammed Lamkanfi, lead investigator and Professor at Ghent University.